About Elsevier

Elsevier is a world-leading provider of information solutions that enhance the performance of science, health, and technology professionals, empowering them to make better decisions, deliver better care, and sometimes make groundbreaking discoveries that advance the boundaries of knowledge and human progress. Elsevier provides web-based, digital solutions — among them ScienceDirect, Scopus, Elsevier Research Intelligence and ClinicalKey — and publishes over 2,000 journals, including The Lancet and Cell, and more than 33,000 book titles, including a number of iconic reference works. Elsevier is part of RELX Group plc, a world-leading provider of information solutions for professional customers across industries.

About the PATHPrimer Team

Our authors are thought leaders in the field of pathology, each contributing a lifetime of subspecialty expertise to the PATHPrimer learning experience. Each of our authors draw on a lifetime of experience and personal resources to continue to enrich PATHPrimer with more images, more review questions, and more innovative ways to help master critical Pathology concepts.

Lead Editors

  • Suzanne A. Arinsburg, DO
    Suzanne A. Arinsburg, DO, is an Assistant Professor in the Icahn School of Medicine Department of Pathology at Mount Sinai Hospital. She is currently the Assistant Director of Blood Bank and Transfusion Services, overseeing the blood bank and cellular therapy laboratories and the apheresis service. Dr. Arinsburg is board-certified in blood bank and transfusion medicine and clinical pathology. She has authored book chapters and articles in the field of transfusion medicine and was a lead editor for the Clinical Pathology Board Review book. She received her undergraduate degree from Binghamton University and her DO from the New York College of Osteopathic Medicine. She went on to complete her residency in clinical pathology at Weill Cornell Medical College and her fellowship in blood banking and transfusion medicine at the New York Blood Center and the Columbia University Medical Center.

    Affiliation: Assistant Professor, Department of Pathology, Icahn School of Medicine at Mount Sinai, and Assistant Director of Blood Bank and Transfusion Services, Mount Sinai Hospital, New York, NY
  • Martin H. Bluth, MD, PhD
    Dr. Bluth completed his MD and his PhD in immunology at the SUNY Downstate Medical Center, his residency in clinical pathology at Kings County Hospital, his fellowship training in transfusion medicine at the New York Blood Center, and his post-doctoral fellowship in tumor markers at the Veteran’s Affairs Medical Center in New York. He maintains board certification in his disciplines. He currently serves as the Chief Medical Officer for Consolidated Laboratory Management Systems, and holds positions as Professor of Pathology at Wayne State University School of Medicine and Medical Director of Pathology Laboratories for Michigan Surgical Hospital. Dr. Bluth serves as National Medical Director for Kids Kicking Cancer and as Associate Editor for Henry’s Clinical Diagnosis and Management by Laboratory Methods, the premier textbook on clinical pathology and laboratory medicine. He holds the position of Editor in Chief for three peer-reviewed medical journals and reviews for over two dozen other journals in various disciplines. Dr. Bluth is also a serial entrepreneur in maturing novel biomarkers, devices, and therapeutics (www.bluthbio.com); serves on numerous committees (including the Michigan State Medical Society Committee on Health Care Quality, Efficiency and Economics); has authored over 200 publications; and is sought after for speaking engagements worldwide.

    Affiliation: Professor, Department of Pathology, Wayne State University School of Medicine, Medical Director of Pathology Laboratories for Michigan Surgical Hospital, Chief Medical Officer for Consolidated Laboratory Management Systems.
  • David G. Hicks, MD
    David G. Hicks, MD, is the Director of Surgical Pathology at the University of Rochester Medical Center. Dr. Hicks’ innovative approaches to improving efficiency and quality in surgical pathology have been highlighted in publications and invited lectures sponsored by national pathology organizations. His organizational interests are in the development of a subspecialty-based surgical pathology system, combining disease-specific diagnostic and prognostic expertise with translational research based on organ systems and disease categories. Dr. Hicks’ first research interest was in bone pathology. He received NIH funding to study the effects of lead on the epiphyseal plate, and collaborated on related studies with faculty in the Department of Orthopaedics at the University of Rochester. He published extensively on metabolic and neoplastic bone disorders. While Director of Surgical Pathology and Co-director of the Morphologic Molecular Pathology translation research resource at the Cleveland Clinic, he expanded his interests in breast pathology, with particular focus on prognostic molecular markers in breast cancer and development of advanced tissue-based diagnostic techniques.

    Affiliation: Director of Surgical Pathology, University of Rochester Medical Center, Rochester, NY
  • Alexandros D. Polydorides, MD, PhD
    Dr. Alexandros D. Polydorides is an assistant professor of pathology at the Mount Sinai School of Medicine and an attending pathologist in the Division of Gastrointestinal Pathology at the Mount Sinai Hospital in New York City. He has authored or co-authored numerous peer-reviewed publications and book chapters, and regularly presents abstracts at international pathology meetings where he is often invited to lecture on various topics in gastrointestinal pathology. A native of Athens, Greece, Dr. Polydorides graduated from Princeton University (Molecular Biology and Biomedical Engineering) in 1995 and the Tri-Institutional MD/PhD program in 2003, obtaining his MD from Weil Cornell Medical College and his PhD from Rockefeller University where he studied neuronal RNA-binding proteins in the laboratory of Dr. Robert B. Darnell. He completed his Residency in Anatomic Pathology at New York Presbyterian Hospital/Weil Cornell Medical Center in 2006, followed by fellowships in oncologic surgical pathology at Memorial Sloan-Kettering Cancer Center and in gastrointestinal pathology at the University of Michigan where he trained under Dr. Henry D. Appelman. Dr. Polydorides has been the recipient of numerous awards and distinctions throughout his academic career. He is an active member of many academic pathology societies and a regular reviewer of articles submitted for publication to distinguished pathology journals. He continues to collaborate as an investigator in many funded research programs as well as to participate in the teaching and training of medical students, residents, and fellows.

    Affiliation: Assistant Professor of Pathology, Mount Sinai School of Medicine; Attending Pathologist, Division of Gastrointestinal Pathology, Mount Sinai Hospital, New York, NY
  • Kristie L. White, MD, MAEd
    Kristie White, MD, MAEd, is the Director of Hematology at the University of California, San Francisco (UCSF), Benioff Children’s Hospital and the Director of Residency Training for Clinical Pathology at UCSF. She completed a master’s degree in education at the University of California, Berkeley, to gain expertise in educational methods. Dr. White’s research interests include developing new technologies for use in medical education, with an emphasis on the development of assessment methods and curricula for pathology resident education. Her clinical activities include diagnostic hematopathology and hematology, with a focus on pediatric hematopathology.

    Affiliation: Director, Residency Training Program; Director, Hematology Laboratory at Mission Bay; Assistant Clinical Professor Department of Laboratory Medicine, University of California, San Francisco, CA

Associate Editors

  • Matthew S. Karafin, MD, MS
    Dr. Matthew Karafin has been an Associate Medical Director for the BloodCenter of Wisconsin since 2012, after completing his transfusion medicine fellowship and pathology residency at the Johns Hopkins Hospital. Dr. Karafin’s major clinical responsibilities include managing the blood bank and the therapeutic apheresis service for the Froedtert Hospital/Medical College of Wisconsin in Milwaukee, and educating residents and fellows in transfusion medicine. Dr. Karafin is a passionate advocate for patients with sickle cell disease; he directs the red cell exchange program for the Adult Sickle Cell Clinic at Froedtert Hospital, and his research focus of the last three years has been in improving transfusion support for patients with sickle cell disease.

    Affiliation: Associate Medical Director, Medical Sciences Institute: BloodCenter of Wisconsin. Assistant Professor of Pathology, Medical College of Wisconsin, Milwaukee, WI
  • Cheryl Mather, MD
    Dr. Cheryl Mather was the Molecular Genetic Pathology Fellow at the University of California, San Francisco. She trained in anatomic pathology, clinical pathology, and gastrointestinal pathology at the University of Washington in Seattle. While in Seattle, Dr. Mather completed an acting directorship in the clinical microbiology laboratory and published work on the identification of mycobacteria and vancomycin-intermediate Staphylococcus aureus using matrix-assisted laser desorption-ionization/time-of-flight mass spectrometry (MALDI-TOF MS). She has also worked on the identification of oncogenic viruses in targeted sequencing data.

    Affiliation: Assistant Clinical Professor, Department of Laboratory Medicine and Pathology, University of Alberta, Alberta, Canada

Section Leads

Bone

  • David G. Hicks, MD
    David G. Hicks, MD, is the Director of Surgical Pathology at the University of Rochester Medical Center. Dr. Hicks' innovative approaches to improving efficiency and quality in surgical pathology have been highlighted in publications and invited lectures sponsored by national pathology organizations. His organizational interests are in the development of a subspecialty-based surgical pathology system, combining disease-specific diagnostic and prognostic expertise with translational research based on organ systems and disease categories. Dr. Hicks' first research interest was in bone pathology. He received NIH funding to study the effects of lead on the epiphyseal plate, and collaborated on related studies with faculty in the Department of Orthopaedics at the University of Rochester. He published extensively on metabolic and neoplastic bone disorders. While Director of Surgical Pathology and Co-director of the Morphologic Molecular Pathology translation research resource at the Cleveland Clinic, he expanded his interests in breast pathology, with particular focus on prognostic molecular markers in breast cancer and development of advanced tissue-based diagnostic techniques.

    Affiliation: Director of Surgical Pathology, University of Rochester Medical Center, Rochester, NY

Breast

  • Linda M. Schiffhauer, MD
    Attending Surgical Pathologist, Breast Subspecialty Service; Associate Director, Pathology Residency Program; Co-Director, Surgical Pathology Resident Rotation; Associate Professor of Pathology, Department of Pathology and Laboratory Medicine, University of Rochester Medical Center and School of Medicine and Dentistry, Rochester, NY

Cardiovascular and Thoracic

Clinical Chemistry

  • Melkon DomBourian, MD
    Dr. Melkon G. DomBourian is an Assistant Professor of Pathology at the University of Colorado. He serves as the Medical Director of Clinical Chemistry and Point of Care Testing as well as the Associate Medical Director of Transfusion Medicine Services at the Children’s Hospital Colorado. He graduated from the University of Wisconsin School of Medicine and completed a residency in anatomic and clinical pathology at the University of Colorado. He then completed fellowships in chemical pathology and blood banking/transfusion medicine at the William Beaumont Hospital in Royal Oak, MI. He is board-certified in anatomic pathology, clinical pathology, chemical pathology, and blood banking/transfusion medicine.

    Affiliation: Medical Director, Clinical Chemistry and Point of Care Testing; Associate Medical Director, Transfusion Medicine Services Children’s Hospital Colorado; Assistant Professor of Pathology, University of Colorado School of Medicine, Aurora, CO.

Cytopathology

Dermatopathology

  • Bruce Smoller, MD
    Professor and Chair, Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY

Forensics and Autopsy

  • Rebecca Irvine, MD
    Senior Staff Specialist, Forensic Pathology, Department of Forensic Medicine, Sydney, Australia
  • Harold Sanchez, MD
    Associate Chief of Pathology, Hospital of Central Connecticut, New Britain, CT

Gastrointestinal

  • Alexandros D. Polydorides, MD, PhD
    Dr. Alexandros D. Polydorides is an assistant professor of pathology at the Mount Sinai School of Medicine and an attending pathologist in the Division of Gastrointestinal Pathology at the Mount Sinai Hospital in New York City. He has authored or co-authored numerous peer-reviewed publications and book chapters, and regularly presents abstracts at international pathology meetings where he is often invited to lecture on various topics in gastrointestinal pathology. A native of Athens, Greece, Dr. Polydorides graduated from Princeton University (Molecular Biology and Biomedical Engineering) in 1995 and the Tri-Institutional MD/PhD program in 2003, obtaining his MD from Weil Cornell Medical College and his PhD from Rockefeller University where he studied neuronal RNA-binding proteins in the laboratory of Dr. Robert B. Darnell. He completed his Residency in Anatomic Pathology at New York Presbyterian Hospital/Weil Cornell Medical Center in 2006, followed by fellowships in oncologic surgical pathology at Memorial Sloan-Kettering Cancer Center and in gastrointestinal pathology at the University of Michigan where he trained under Dr. Henry D. Appelman. Dr. Polydorides has been the recipient of numerous awards and distinctions throughout his academic career. He is an active member of many academic pathology societies and a regular reviewer of articles submitted for publication to distinguished pathology journals. He continues to collaborate as an investigator in many funded research programs as well as to participate in the teaching and training of medical students, residents, and fellows.

    Affiliation: Assistant Professor of Pathology, Mount Sinai School of Medicine; Attending Pathologist, Division of Gastrointestinal Pathology, Mount Sinai Hospital, New York, NY

General Topics

  • Alexandros D. Polydorides, MD, PhD
    Dr. Alexandros D. Polydorides is an assistant professor of pathology at the Mount Sinai School of Medicine and an attending pathologist in the Division of Gastrointestinal Pathology at the Mount Sinai Hospital in New York City. He has authored or co-authored numerous peer-reviewed publications and book chapters, and regularly presents abstracts at international pathology meetings where he is often invited to lecture on various topics in gastrointestinal pathology. A native of Athens, Greece, Dr. Polydorides graduated from Princeton University (Molecular Biology and Biomedical Engineering) in 1995 and the Tri-Institutional MD/PhD program in 2003, obtaining his MD from Weil Cornell Medical College and his PhD from Rockefeller University where he studied neuronal RNA-binding proteins in the laboratory of Dr. Robert B. Darnell. He completed his Residency in Anatomic Pathology at New York Presbyterian Hospital/Weil Cornell Medical Center in 2006, followed by fellowships in oncologic surgical pathology at Memorial Sloan-Kettering Cancer Center and in gastrointestinal pathology at the University of Michigan where he trained under Dr. Henry D. Appelman. Dr. Polydorides has been the recipient of numerous awards and distinctions throughout his academic career. He is an active member of many academic pathology societies and a regular reviewer of articles submitted for publication to distinguished pathology journals. He continues to collaborate as an investigator in many funded research programs as well as to participate in the teaching and training of medical students, residents, and fellows.

    Affiliation: Assistant Professor of Pathology, Mount Sinai School of Medicine; Attending Pathologist, Division of Gastrointestinal Pathology, Mount Sinai Hospital, New York, NY

Genitourinary

  • Brian D. Robinson, MD
    Assistant Professor of Pathology & Laboratory Medicine, Assistant Professor of Pathology in Urology, Weill Cornell Medical College/New York-Presbyterian Hospital, New York, NY

Gynecological

  • Rochelle Simon, MD
    Associate Professor of Pathology, The George Washington University Medical Center, Washington, DC

Head & Neck / Endocrine

Hematology, Hemostasis, and Thrombosis

  • Jeffrey S. Jhang, MD
    Dr. Jeffrey Jhang is an Associate Professor of Pathology at the Icahn School of Medicine at Mount Sinai in New York and the Director of Blood Bank and Transfusion Service for the Mount Sinai Health System. Dr. Jhang provides medical and administrative leadership as the director of the blood bank, apheresis unit, cellular therapy laboratory, and hematology and coagulation laboratory. In this role, he has enhanced the quality, safety, and efficiency of transfusion medicine and hematology services. The harmful effects, complications, and poor outcomes of blood transfusion have been the focus of his research. He has studied the negative effects of long-term storage of red blood cells in both human and mouse models of transfusion, as well as characteristics of blood donors (e.g., G6PD deficiency, hemoglobinopathies) that may be harmful to blood transfusion recipients. The goal of his research is to provide clinical evidence either in support of or against using apheresis in the treatment of human diseases. He has reported on the safety and effectiveness of apheresis in Wilson disease, heart transplant rejection, and kidney transplant rejection. In addition to his local leadership roles, he also provides leadership in the global pathology community through his professional service on national and international pathology committees and through his work in the development of educational resources. As a part of the FACT, CAP, and AABB committees, he has co-written and provided subject matter expertise on international standards for laboratory testing and stem cell collection. The FACT standards, CLSI and ISO documents, and AABB standards are used throughout the world to ensure that laboratories are providing the highest quality services. He has edited and authored book chapters and web resources that have been useful to pathologists, residents, and fellows. He is a co-editor of the Clinical Pathology Board Review book, also published by Elsevier.

    Affiliation: Associate Professor of Pathology, Icahn School of Medicine at Mount Sinai; Director, Blood Bank and Transfusion Services, Mount Sinai Health System, New York, NY

Hematopathology

  • Jeremy C. Wallentine, MD
    Hematopathologist and Director of Molecular Diagnostics, Intermountain Healthcare Central Region Department of Pathology, Salt Lake City, UT
  • Kristie L. White, MD, MAEd
    Kristie White, MD, MAEd, is the Director of Hematology at the University of California, San Francisco (UCSF), Benioff Children’s Hospital and the Director of Residency Training for Clinical Pathology at UCSF. She completed a master’s degree in education at the University of California, Berkeley, to gain expertise in educational methods. Dr. White's research interests include developing new technologies for use in medical education, with an emphasis on the development of assessment methods and curricula for pathology resident education. Her clinical activities include diagnostic hematopathology and hematology, with a focus on pediatric hematopathology.

    Affiliation: Director, Residency Training Program; Director, Hematology Laboratory at Mission Bay; Assistant Clinical Professor Department of Laboratory Medicine, University of California, San Francisco, CA

Immunology

  • Patrick Michael Long, PhD
    P. Michael Long, PhD, is Associate Professor of Pathology at the Wayne State University School of Medicine and Technical Director of Immunodiagnostics at the Detroit Medical Center University Laboratory. He received his undergraduate degree from Villanova University and his master’s degree from Seton Hall University. He received his PhD in Immunology from the Wayne State School of Medicine and completed a tumor immunology fellowship at the Mayo Clinic Graduate School of Medicine in Rochester, MN. Specialty: Immunodeficiency, Autoimmunity, and Infectious Diseases.

    Affiliation: Technical Director of Immunodiagnostics, Detroit Medical Center University Laboratory; Associate Professor, Department of Pathology, Wayne State School of Medicine, Detroit, MI

Laboratory Management and Clinical Laboratory Informatics

  • Paul Tranchida, MD
    Paul Tranchida, MD, is currently employed at the Detroit Medical Center. He graduated from the Wayne State University School of Medicine and did his anatomic and clinical pathology residencies at the Detroit Medical Center. He subsequently completed fellowships in pathology informatics and cytopathology at the Henry Ford Health System, and then returned to the Detroit Medical Center to complete one final fellowship in surgical pathology before joining the staff.

    Affiliation: Assistant Professor, Department of Pathology, Wayne State University School of Medicine, Detroit, MI

Medical Microbiology

  • Cheryl Mather, MD
    Dr. Cheryl Mather was the Molecular Genetic Pathology Fellow at the University of California, San Francisco. She trained in anatomic pathology, clinical pathology, and gastrointestinal pathology at the University of Washington in Seattle. While in Seattle, Dr. Mather completed an acting directorship in the clinical microbiology laboratory and published work on the identification of mycobacteria and vancomycin-intermediate Staphylococcus aureus using matrix-assisted laser desorption-ionization/time-of-flight mass spectrometry (MALDI-TOF MS). She has also worked on the identification of oncogenic viruses in targeted sequencing data.

    Affiliation: Assistant Clinical Professor, Department of Laboratory Medicine and Pathology, University of Alberta, Alberta, Canada
  • Susan Whittier, PhD, ABMM
    Dr. Susan Whittier, a board-certified doctoral-level scientist, is Director of the Clinical Microbiology Service at the NewYork-Presbyterian Hospital/Columbia University Medical Center and an Associate Professor of Clinical Pathology and Cell Biology at the Columbia University Medical Center. She received her PhD in microbiology and immunology from Hahnemann University in Philadelphia and went on to do her fellowship at UNC Hospital in Chapel Hill, NC. Dr. Whittier is on several editorial boards, has authored chapters on bacterial identification, and has published more than 70 research articles. Her areas of interest include emerging antibiotic resistance, implementation of molecular techniques in the clinical lab, cost-effective laboratory algorithms, detection of C. difficile, and the microbiology of cystic fibrosis patients. She is the former president of the NYC branch of the American Society of Microbiology and is a frequent lecturer at both national and international microbiology and infectious disease symposia.

    Affiliation: Director, Clinical Microbiology Service, NewYork-Presbyterian/Columbia University Medical Center; Associate Professor of Clinical Pathology and Cell Biology, Department of Pathology and Cell Biology, Columbia University, New York, NY

Molecular

  • Aaron Auerbach, MD, MPH
    Senior Pathologist, Department of Hematopathology, Joint Pathology Center; Director of Hematacor for Bostwick Laboratories, Silver Spring, MD

Molecular Pathology and Cytogenetics

  • Mark D. Ewalt, MD
    Mark D. Ewalt, MD, is Assistant Professor of Pathology and Laboratory Medicine and the Associate Program Director of the Molecular Genetic Pathology Fellowship at Cedars-Sinai Medical Center. Dr. Ewalt is certified in hematopathology and molecular genetic pathology, and he is interested in merging these disciplines to better understand the molecular diagnostics of myeloid neoplasms. He is actively involved in the hematopathology subdivision of the Association for Molecular Pathology (AMP) and was recently elected to serve as a member of its Teaching and Education Committee (TEC).

    Affiliation: Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA

Neuropathology

  • Gabrielle Yeaney, MD
    Division of Neuropathology, RT Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH

Pancreas, Biliary, Liver

  • Huaibin Mabel Ko, MD
    Assistant Professor, Division of Gastrointestinal Pathology, Department of Pathology, The Mount Sinai Hospital, New York, NY

Pediatrics

  • Jessica Comstock, MD
    Pediatric Pathologist, University of Utah Department of Pathology, Division of Pediatric Pathology, Primary Children’s Hospital, Salt Lake City, UT
  • Angelica R. Putnam, MD
    Associate Professor of Pathology, University of Utah School of Medicine, Division of Pediatric Pathology, Primary Children’s Hospital, Salt Lake City, UT

Soft Tissue

  • Matthew R. Lindberg, MD
    Assistant Professor, Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR

Toxicology

  • Y. Victoria Zhang, PhD, DABCC
    Y. Victoria Zhang, PhD, DABCC, is an Associate Professor in the Department of Pathology and Laboratory Medicine at the University of Rochester Medical Center. She is Associate Director of Clinical Pathology, Director of the Clinical Mass Spectrometry and Toxicology Laboratory, and Associate Director of the Clinical Chemistry Laboratory at the Strong Memorial Hospital in Rochester. Dr. Zhang completed her clinical chemistry fellowship training at Boston Children’s Hospital, Harvard Medical School. Her research interests are in clinical applications of mass spectrometry, transitioning of late-phase discovery and ‑omics biomarkers to clinical services, and biomarker discovery for early diagnosis of disease and prognosis using ‑omics technologies. Dr. Zhang is the founding chair of the AACC Mass Spectrometry and Separation Sciences divisions, leading the national effort to enhance clinical applications of mass spectrometry for precision medicine. She is the faculty chair for the AACC Online Certificate Programs for the introductory and troubleshooting programs for LC-MS/MS. Dr. Zhang is also the chair for the AACC Asian Pacific Working Group to lead efforts to enhance the quality and practice of clinical chemistry in this region.

    Affiliation: Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY

Transfusion Medicine

  • Tammon Nash, MD
    Tammon A. Nash, MD, MS, is the System Blood Bank Medical Director for the Detroit Medical Center and Assistant Professor at Wayne State University, Detroit, MI. She is an anatomic and clinical pathology board-certified pathologist with specialty training in transfusion medicine. After completing a transfusion medicine fellowship at the BloodCenter of Wisconsin, she was a Robert Wood Johnson Clinical Scholar at the University of Michigan, Ann Arbor. Her research interests include expanding the blood donor pool and transfusion care for patients with sickle cell anemia. She has several years of experience in therapeutic apheresis, enjoys teaching residents, and looks forward to contributing more to the field of transfusion medicine.

    Affiliation: System Blood Bank Medical Director, Detroit Medical Center, Detroit, MI
  • Geoffrey Wool, MD, PhD
    Geoffrey Wool, MD, PhD, is an Assistant Professor of Pathology at the University of Chicago. He is the Assistant Medical Director of the blood bank and the Associate Medical Director of the coagulation laboratory. He received his MD and PhD from the University of Chicago. He completed his clinical pathology residency and hematopathology fellowship at the University of California, San Francisco, and his transfusion medicine fellowship at the University of Chicago. Dr. Wool’s clinical interests include optimizing transfusion support for critically ill and hemorrhaging patients through the use of whole blood coagulation testing.

    Affiliation: Assistant Professor, Assistant Director of Blood Bank, Associate Director of Coagulation Laboratory, University of Chicago, Chicago, IL

PATHPrimer Contributing Authors

  • N. Volkan Adsay, MD
    Professor of Pathology & Laboratory Medicine
    Vice-Chair and Director of Anatomic Pathology
    Emory University
    Atlanta, Georgia
  • Vimla Aggarwal, MBBS, FACMG
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Aqeel Ahmed, MD
    Associate Research Scientist
    Cancer Center
    Herbert Irving Comprehensive Cancer Center
    Columbia University Medical Center
    New York, New York
  • Bachir Alobeid, MD
    Professor of Pathology and Cell Biology
    Attending Physician, Pathology
    Columbia University Medical Center
    New York Presbyterian Hospital
    New York, New York
  • Kyle M. Annen, DO
    Kyle M. Annen, DO, is the Medical Director of the Blood Bank and Transfusion Service at Mount Sinai Beth Israel. Dr. Annen’s primary interests are patient blood management, education, and therapeutic apheresis. She is actively involved in the development of a preoperative anemia program, improving patient blood management at her institution, and providing education in coagulation and transfusion medicine for residents, fellows, and medical students. Previously, Dr. Annen was with the BloodCenter of Wisconsin, where she served as Associate Director for the Immunohematology Reference Laboratory and provided consultation to area physicians on challenging transfusion cases. She is an Assistant Professor at the Icahn School of Medicine. Her current research is in patient blood management initiatives and therapeutic apheresis; prior research was in identifying underlying diseases in blood donors with low hemoglobin.
  • Dana Balitzer, MD
    Resident Physician
    Departments of Pathology and Laboratory Medicine
    University of California, San Francisco
    San Francisco, CA
  • Olca Basturk, MD
    Assistant Attending
    Department of Pathology
    Memorial Sloan-Kettering Cancer Center
    New York, New York
  • Alain C. Borczuk, MD
    Professor of Pathology at CUMC and Vice Chairman of Anatomic Pathology
    Columbia University Medical Center
    New York, New York
  • John Cannatella, MD
    Resident Physician
    University of California, San Francisco
    San Francisco, CA
  • Raphael Clynes, MD, PhD
    Associate Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Adriana I. Colovai, PhD, D(ABHI)
    Associate Professor of Clinical Surgery
    Albert Einstein College of Medicine
    Director, Transplant Immunology Laboratory
    Department of Surgery
    Montefiore Medical Center
    Bronx, NY
  • Serge Cremers, PharmD, PhD
    Assistant Professor of Pathology and Cell Biology
    Director, Biomarker Core Laboratory
    Irving Institute for Clinical and Translational Research
    Columbia University Medical Center
    New York, NY
  • Vivette D. D’Agati, MD
    Professor of Pathology & Cell Biology
    Columbia University
    New York, New York
  • Phyllis Della-Latta, (D)ABMM, FAAM
    Director, Clinical Microbiology Service
    Professor of Clinical Pathology in Medicine
    Columbia University Medical Center
    New York-Presbyterian Hospital
    New York, NY
  • Kalpana Devaraj, MD
    Assistant Professor of Pathology
    Anschutz Medical Campus
    University of Colorado
    Denver, CO
  • Tanis C. Dingle, PhD, D(ABMM), FCCM
    Tanis C. Dingle, PhD, is a clinical microbiologist at the Alberta Provincial Laboratory for Public Health. She completed her PhD in microbiology and infectious diseases at the University of Calgary, Canada, under the mentorship of Dr. Glen Armstrong. Dr. Dingle went on to complete a postdoctoral fellowship in clinical and public health microbiology at the University of Washington in Seattle. Prior to her current role, she was Assistant Director of Clinical Microbiology for the Mount Sinai Health System in New York. Her research interests include antimicrobial susceptibility testing and resistance mechanism determination, rapid microorganism identification methods, and Clostridium difficile pathogenesis and diagnostics.
  • Michelle Don, MD
    Michelle Don, MD, is currently completing her residency in both anatomic and clinical pathology at the Cedars-Sinai Medical Center. Her current interests include hematopathology, surgical pathology, and molecular pathology.
  • Jonathan H. Esensten MD, PhD
    Jonathan H. Esensten, MD, PhD, is a Leukemia & Lymphoma Society postdoctoral fellow in the laboratory of Dr. Wendell Lim at the University of California, San Francisco (UCSF). He works on synthetic biology approaches to improve anti-cancer T-cell therapies. He is the Medical Director for the regulatory T-cell manufacturing group at the HICTF and GMP Facility at UCSF. Dr. Esensten completed his residency in clinical pathology at UCSF and a fellowship in transfusion medicine in the joint UCSF/Blood Centers of the Pacific program.
  • Richard O. Francis, MD, PhD
    Assistant Professor of Pathology and Cell Biology
    Director, Special Hematology and Coagulation Laboratory
    Columbia University Medical Center
    NewYork-Presbyterian Hospital
    New York, NY
  • Valerie A. Fitzhugh, MD
    Assistant Professor of Pathology and Laboratory Medicine
    Rutgers, The State University of New Jersey – New Jersey Medical School
    Attending Pathologist
    Pathology and Laboratory Medicine
    University Hospital
    Newark, New Jersey
  • James E. Goldman, MD, PhD
    Neuropathology Fellow
    Columbia University
    New York, New York
  • Kevin Ha, DO
    University of Minnesota Medical Center, Pathology
    Minneapolis, MN
  • Diane Hamele-Bena, MD
    Assistant Professor of Pathology and Cell Biology
    Columbia University
    New York, New York
  • Lara R. Harik, MD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • Rebecca Harris, MD
    Assistant Director, Microbiology
    Assistant Professor, Pathology
    Mount Sinai Health System
    Icahn School of Medicine at Mount Sinai
    New York, NY
  • Debra S. Heller, MD
    Professor of Pathology
    Rutgers New Jersey Medical School
    Attending Physician
    Pathology & Laboratory Medicine
    University Hospital
    Newark, New Jersey
  • Leal C. Herlitz, MD
    Associate Professor of Pathology & Cell Biology
    Columbia University
    New York, New York
  • Hanina Hibshoosh, MD
    Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • Eldad A. Hod, MD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Paul R. Hosking, MD
    Assistant Professor of Pathology
    Medical College of Wisconsin
    Froedtert Hospital
    Milwaukee, WI
  • Richard C. Huard, PhD, D(ABMM)
    Assistant Professor of Clinical Pathology
    Columbia University Medical Center
    New York, NY
  • Raquel Walsh Jahnke, DO, MBA
    Hematopathology Fellow
    University of Minnesota Medical Center
    Minneapolis, MN
  • Vaidehi Jobanputra, PhD, MS
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Adrienne Jordan, MD
    Dr. Jordan is a board-certified anatomic and clinical pathologist. She serves as Assistant Laboratory Director at the New York Eye and Ear Infirmary of Mount Sinai and as Assistant Professor of Pathology at the Icahn School of Medicine at Mount Sinai. She has subspecialty expertise in dermatopathology and ophthalmologic pathology, and has experience in clinical laboratory testing for a broad range of human diseases. Dr. Jordan’s research interests are in cutaneous and ocular melanocytic neoplasms.
  • Wendy Kadi, DO
    Anatomic Pathology/Clinical Pathology Resident
    Cedars-Sinai Medical Center
    Los Angeles, CA
  • Samer N. Khader, MD
    Assistant Professor of Pathology
    Associate Director, Cytopathology Fellowship Program
    Albert Einstein College of Medicine / Montefiore Medical Center
    Bronx, New York
  • Priyadarshini Kumar, MD
    Anatomic Pathology/Clinical Pathology Resident, Chief Resident
    Cedars-Sinai Medical Center
    Los Angeles, CA
  • Nicholas Ladwig, MD
    Resident Physician
    University of California, San Francisco
    San Francisco, CA
  • Stephen M. Lagana, MD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center and the New York Presbyterian Hospital
    New York, New York
  • Elly Landolfi, MD
    Elly Landolfi, MD, is currently the transfusion medicine fellow at Beaumont Hospital in Michigan. She is board-certified in anatomic pathology and clinical pathology and has pursued fellowship training at Wayne State University, completing the hematopathology and cytopathology fellowship programs. Dr. Landolfi has an interest in medical education and truly enjoys each opportunity to mentor residents and medical students.
  • John C. Lee, MD
    Assistant Professor of Pathology and Laboratory Medicine
    Boston University Medical Center
    Boston, Massachusetts
  • Brynn Levy, MSc(Med), PhD, FACMG
    Professor of Pathology and Cell Biology
    Co-Director, Personalized Genomic Medicine
    Columbia University Medical Center
    Director, Genetics Laboratory
    NewYork-Presbyterian Hospital
    New York, NY
  • Mahesh M. Mansukhani, MD
    Associate Professor of Pathology and Cell Biology
    Medical Director, CUMC Personalized Genomic Medicine Laboratory
    Columbia University Medical Center
    New York, New York
  • Charles C. Marboe, MD
    Professor of Pathology and Cell Biology at CUMC
    Department of Pathology and Cell Biology
    Columbia University Medical Center and The New York Presbyterian Hospital
    New York, New York
  • Glen S. Markowitz, MD
    Professor of Pathology & Cell Biology
    Columbia University
    New York, New York
  • Daniel Martig, MD
    Resident Physician
    University of California, San Francisco
    San Francisco, CA
  • Lorenzo Memeo, MD
    Director of the Pathology Unit
    Department of Experimental Oncology
    Mediterranean Institute of Oncology
    Scientific Director
    Iom Ricerca SRL
    Catania, Italy
  • Roger K. Moreira, MD
    Senior Associate Consultant and Assistant Professor
    Department of Laboratory Medicine and Pathology
    Mayo Clinic
    Rochestor, Minnesota
  • Vundavalli V. Murty, PhD
    Associate Professor of Pathology and Cell Biology
    Columbia University Medical Center
    Director, Cancer Cytogenetics
    NewYork-Presbyterian Hospital
    New York, NY
  • Peter L. Nagy, MD, PhD
    Assistant Professor of Pathology and Cell Biology
    Director of Clinical Next-Generation Sequencing
    Columbia University Medical Center
    New York, NY
  • Ali Naini, PhD
    Associate Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Jennifer V. Nguyen, MD
    Assistant Professor of Clinical Dermatology
    Perelman School of Medicine at the University of Pennsylvania
    Philadelphia, Pennsylvania
  • Volker Nickeleit, MD
    Professor of Pathology
    Director: Division of Nephropathology
    Department of Pathology and Laboratory Medicine
    The University of North Carolina at Chapel Hill
    Chapel Hill, North Carolina
  • Kathleen M. O’Toole, MD
    Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • May Parisien, MD
    Special Lecturer of Clinical Pathology
    Columbia University
    New York, New York
  • Sapna Patel, MD
    Sapna Patel, MD, is an Anatomic Pathology/Clinical Pathology Resident at the University of Rochester Department of Pathology and Laboratory Medicine and a Hematopathology Fellow at the University of Pennsylvania.
  • Snehalkumar Patel, MD, PhD
    Snehalkumar Patel, MD, PhD, attended Vanderbilt University for his undergraduate studies where he majored in mathematics and biomedical engineering. Dr. Patel became fascinated with gene regulation at the level of post- and co-transcriptional mRNA processing in his first college biology class, which led him to pursue a combined degree program at the University of Illinois at Urbana-Champaign. Dr. Patel’s graduate research culminated in one of the first functional demonstrations that pre-mRNA splicing is a co-transcriptional event for the vast majority of genes in advanced eukaryotes. During his medical training, Dr. Patel realized that pathology was an excellent career choice for those interested in integrating basic science and medicine. He entered residency training in anatomic and clinical pathology at the Cedars-Sinai Medical Center, where he became intrigued by molecular pathology in his very first rotation. Dr. Patel recently completed his training as a clinical scholar and a molecular genetic pathology fellow at Cedars-Sinai Medical Center and is embarking on a position as a molecular pathologist at the National Cancer Institute, Laboratory of Pathology.
  • Karl H. Perzin, MD
    Professor Emeritus of Clinical Surgical Pathology
    Consulting Pathologist, Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • Michael A. Pesce, PhD
    Professor Emeritus of Pathology and Cell Biology
    Columbia University Medical Center
    NewYork-Presbyterian Hospital
    New York, NY
  • Alex J. Rai, PhD, DABCC, FACB
    Associate Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Fabrizio Remotti, MD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • Helen Remotti, MD
    Assistant Professor of Clinical Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • Heidrun Rotterdam, MD
    Professor Emeritus of Pathology and Cell Biology
    Senior Lecturer
    Department of Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • Adam I. Rubin, MD
    Assistant Professor of Dermatology
    Assistant Professor of Dermatology in Pediatrics
    Assistant Professor of Dermatology in Pathology and Laboratory Medicine
    Hospital of the University of Pennsylvania
    The Children’s Hospital of Philadelphia
    Perelman School of Medicine at the University of Pennsylvania
    Philadelphia, Pennsylvania
  • Suthinee Rutnin, MD
    International Dermatopathology Observer
    Hospital of the University of Pennsylvania
    Philadelphia, Pennsylvania
    Clinical instructor
    Division of dermatology, Faculty of Medicine
    Ramathibodi Hospital, Mahidol University
    Bangkok, Thailand
  • Katie Sackett, DO, MS
    Blood Banking and Transfusion Medicine Fellow
    Department of Laboratory Medicine and Pathology
    University of Minnesota Medical Center
    Minneapolis, MN
  • Marcela Salomao, MD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center/ New York Presbyterian Hospital
    New York, New York
  • Anjali Saqi, MD, MBA
    Associate Professor of Pathology and Cell Biology
    Columbia University Medical Center
    NewYork-Presbyterian Hospital
    New York, NY
  • Joseph Schwartz, MD, PhD
    Associate Professor of Pathology & Cell Biology
    Columbia University Medical Center
    Director, Transfusion Medicine & Cellular Therapy
    NewYork-Presbyterian Hospital
    New York, NY
  • Jorge L. Sepulveda, MD, PhD
    Associate Professor of Pathology and Cell Biology
    Associate Medical Director of Clinical Laboratories
    Columbia University Medical Center
    NewYork-Presbyterian Hospital
    New York, NY
  • Harsharan K. Singh, MD
    Professor of Pathology
    Director of Electron Microscopy Services
    Department of Pathology and Laboratory Medicine
    The University of North Carolina at Chapel Hill
    Chapel Hill, North Carolina
  • Anthony N. Sireci, MD, MSc
    Assistant Professor of Clinical Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Jon J. Smith, MD
    Forensic Pathologist
    Department of Medicine
    Ventura County Medical Center
    Chief Medical Examiner
    Ventura County Medical Examiner Office
    Ventura, California
  • Patrice F. Spitalnik, MD
    Associate Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Steven L. Spitalnik, MD
    Professor & Vice-Chairman of Clinical Pathology & Cell Biology
    Columbia University Medical Center
    Medical Director, Clinical Laboratories
    New York-Presbyterian Hospital
    New York, New York
  • M. Barry Stokes, MD
    Associate Professor of Pathology & Cell Biology
    Columbia University
    New York, New York
  • Brie Stotler, MD, MPH
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    Assistant Director of Hospital Core Laboratory
    NewYork-Presbyterian Hospital
    New York, NY
  • Matthias J. Szabolcs, MD
    Professor of Clinical Pathology
    Columbia University
    New York, New York
  • Yvette C. Tanhehco, MD, MS, PhD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    Assistant Director, Transfusion Medicine
    NewYork-Presbyterian Hospital
    New York, NY
  • Kurenai Tanji, MD, PhD
    Professor of Clinical Pathology and Cell Biology (in Neurology)
    Columbia University
    New York, New York
  • Harsh M. Thaker, MD, PhD
    Vice Chair, Department of Pathology
    Icahn School of Medicine at Mount Sinai
    Mount Sinai Health System
    New York, New York
  • Nicole Therrien, MD
    Resident Physician
    University of California, San Francisco
    San Francisco, CA
  • Andrew Turk, MD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, New York
  • Efsevia Vakiani, MD, PhD
    Assistant Attending, Pathology
    Memorial Sloan-Kettering Cancer Center
    New York, New York
  • Julio A. Valentín, MD
    Neuropathology Fellow
    Columbia University
    New York, New York
  • Elena-Rodica Vasilescu, MD
    Assistant Professor of Clinical Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • George Vlad, PhD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    New York, NY
  • Xiao-Jun Wei, MD
    Assistant Professor of Pathology
    New York University Langone Medical Center
    New York, New York
  • Kwun Wah Wen, MD, PhD
    Resident Physician
    University of California, San Francisco
    San Francisco, CA
  • Tilla S. Worgall, MD, PhD
    Assistant Professor of Pathology and Cell Biology
    Department of Pediatrics
    Institute of Human Nutrition
    Columbia University Medical Center
    New York, NY
  • Fann Wu, MD, PhD
    Assistant Professor of Pathology and Cell Biology
    Columbia University Medical Center
    Chief, Molecular Diagnostic & Epidemiology
    Clinical Microbiology Services
    New York-Presbyterian Hospital
    New York, NY
  • Angela J. Yoon, DDS, MPH, MAMSc
    John W. Richter Associate Prof. of Oral Pathology at CUMC
    Division of Oral & Maxillofacial Pathology
    Columbia University
    New York, New York
Amirsys